His foundation shifted focus to one goalcuring Steve Kirschby supporting one of the few scientists looking at the disease. Once the Phase 2 result came out, it should have been embraced by doctors. Today, if we follow the CDC advice, nearly 100,000 people a month will die from COVID. This site requires JavaScript to run correctly. Opinion: The urgency for vaccinations | The Northside Sun It should be crystal clear to everyone that the current CDC guidelines for treating COVID aren't working. Fluvoxamine is used commonly to treat obsessive-compulsive disorder (OCD), social anxiety disorder and depression. skirsch.io. It could do nothing. There were IRB rules that required the 65 patients to be listed in the diagrams and charts. The sooner you start, the better the outcomes. It is very safe: There is no evidence fluvoxamine is harmful and led to a worse outcome. It is very important to educate doctors because most people rely on their doctors for advice. Compulsive hand washing? Over the summer, the conflict reached his most recent startup, M10. So the drug had no chance of working (since there were no events), so the trial was stopped for futility, NOT because the drug doesnt work. Ivermectin has been falsely promoted as a covid treatmentbut for those who use the drug legitimately, seeing it become a piece of anti-vaccine misinformation is disconcerting. Steve Kirsch cut the check, which allowed Dr. Lenze to finish recruiting the 152 patients he needed for his trial. I took it myself at that dosage and noticed zero side effects. Current Early Covid treatment from Steve Kirsch (infection, doctor Theres nothing there.). If you continue to get this message, Ive used it personally at 50mg twice a day and experience no adverse events at all. Some countries dont have fluvoxamine so this is the alternative. See this. Steve wanted to say, Look, Ive got all these famous [infectious disease] docs and researchers, and they all say give fluvoxamine a chance, Judith Feinberg, one of the former CETF advisory board members and vice chair of research at the West Virginia University School of Medicine, told me. I must admit that this is an anniversary that snuck It was completed in August. It was tested in coronavirus patients because fluvoxamine has very strong anti-inflammatory properties. In some cases, youd want to taper down the dosage. Also, this drug is only prescribed by psychiatrists so most doctors have no experience whatsoever with the drug. If you have trouble getting a prescription, perhaps you have OCD? The ongoing battle between social-media companies and covid-19 misinformation pushersincluding US president Donald Trumpstepped up again this week thanks to a new viral video. He thinks # killed by vax could be anywhere between 0 and 150K people dead.. Molnupiravir followed patients for only 30 days because they know the drug is dangerous. If you take fluvoxamine, please avoid caffeine while on the drug. Fluvoxamine is an inexpensive drug that has been in use for 37 years and has been used by an estimated 10 million people. 21. Those days are gone. To vet proposals, he recruited a powerhouse advisory board of prominent biologists, drug developers, and clinical researchers, led by world-renowned drug researcher Robert Siliciano of Johns Hopkins. I agreed to do it partially because I respect Bob [Siliciano] so much, and partially because I thought the concept was excellent, said former board member Doug Richman, a prominent HIV drug researcher at the University of California San Diego and former member of the funds scientific advisory board. There is absolutely no evidence that either one of these claims is true, as Morris has carefully documented. Now weve lost the high ground, Morris told me. Talking to Kirsch is an exhausting experience. Always be self aware when using fluvoxamine. We have a bounty of vaccines and more on the way, but drugs that treat the disease are vital too if we want to keep people alive and bring the pandemic under control. Kirsch IDeacon BJHuedo-Medina TBScoboria AMoore TJJohnson BT Initial severity and antidepressant benefits: a meta-analysis of data submitted to the Food and Drug Administration. Some people report mild nausea while on the drug (stops when stop the drug). Steve Kirsch: Vaccine Killing Millions, Treatments, VAERS, 5-Month All this was known back in January 2021 when a key opinion leader panel of experts from NIH, CDC, FDA, academia, and journal editors voted by over 2:1 to recommend that fluvoxamine be recommended to physicians to discuss with patients. My crime? After one or two conversations like that, I got tired of arguing, so I started avoiding his calls.. With covid, 80% of your patient population does just peachy with no treatment at all, just a little bed rest and fluid. Tech millionaire Steve Kirsch went from covid trial funder to Doctors are afraid that even with a 37-year safety record of this drug, that something will go terribly wrong and they will be blamed. Its all about NIH saying it is OK. Medicine today is driven by government opinion, not science. Theyre finding alternative leaders to follow, Morris said. 33. My website. Online Status. Fluvoxamine is way better than Molnupiravir, but the NIH doesnt approve drugs on effectiveness. Steven Todd Kirsch is an American entrepreneur. Part of TV News Archive. That way you can start immediately. We pretty much practice government agency opinion medicine all over the world now, with just a few exceptions. After two weeks (since it was a tight knit community, everyone could see what was happening to the two groups), every track worker who got sick with COVID, demanded the drug. I think so. We don't know why the NIH panel is ignoring fluvoxamine and we aren't allowed to find out. During our first conversation, which turned into a multi-hour Zoom session, Kirsch paced through the rooms of his cavernous house with his phone held at chest level, rarely looking down at the camera. Substitutions. P-value was 10^-14 on that study (done by Dr. Seftel). Seftel used a 50mg BID dosing for 14 days which was one third of the max dose used in the Lenze study. Note that some of these articles are inaccurate. Can a common antidepressant help in the fight against COVID-19? Reason is the hospital gets release from liability if they follow NIH guidelines. That work has yielded one promising candidate, the antidepressant fluvoxamine; other CETF-funded efforts have been less successful. He has a history of giving away some of his millions to good causes, and when COVID-19 began. As of November 13, fluvoxamine has been proven to work in every trial that has published results, including outpatient and inpatient studies. Im sorry to sound so cynical. . He prefers iconoclastic approaches, whether by directly funding asteroid detection or advocating for nuclear power to combat global warming. Its whether Merck can make a killing that matters. They left their recommendation of fluvoxamine at NEUTRAL. But even she was drained by Kirschs constant attempts to override the data. New evidence that toxic "spike protein" component of Covid-19 vaccines The post read: "I will be featured on 60 Minutes this Sunday talking about fluvoxamine as an effective treatment for COVID-19 to prevent hospitalization and death. Steve Kirsch is a high-tech serial entrepreneur based in Silicon Valley. Other drugs in this class include Prozac (fluoxetine), Zoloft (sertraline) and Paxil (paroxetine). It cant be more clear than this. just like ivermectin). The results would, eventually, set Kirsch on a collision course with the scientific establishment. Some countries dont have fluvoxamine so this is the alternative. Still, in the moment, his question threw me, and I stuttered. This was shown to be very tolerable (no side effects in 99% of patients) and extremely effective (no hospitalizations and death if you start it ASAP after first symptoms). The next major effect is that that fluvoxamine activates the sigma-1 receptor. We dont want to feed the anti-vaccine trolls, so we actively suppress clear scientific data. For example all of these combos should have near 100% success against hospitalization, death, and long-haul COVID symptoms: Proxalutamide and fluvoxamine Sadly, doctors and public health officials refuse to instruct patients to seek early treatment. . Online. The alarming article cited the claims of two anti-vaxxers, Steve Kirsch and Dr. Robert Malone. Another CETF grant, though, yielded far more exciting results. You can use fluoxetine as well (aka Prozac). Fluoxetine is just as effective. . JAMA Reports Fluvoxamine as Potential Early Treatment for COVID-19 Fluvoxamine has at least a 30% hospitalization and death benefit. And not zero., Kirsch immediately forwarded the exchange to me and, I suspect, other journalists. Skirsch.io Steve Kirsch Home page Fluvoxamine, COVID, pandemic, . It does not matter how many lives will be saved. Fluvoxamine works on hospitalized patients too, but no US hospital will let you use it (sound familiar? This 1/6 of the dose the FDA has approved for OCD (the labelled indication for fluvoxamine)! Every earlier study of fluvoxamine (such as observational studies) showed it work and the mechanism had been shown. Thirty minutes past the end of our scheduled time, he dropped his phone in the cupholder of his Tesla so that he could keep talking while he ran an errand. A very short op-ed arguing for using fluvoxamine against COVID. In other cases, stop cold turkey. One user reported dilated pupils and increased heart rate (which could be nerves about the dilated pupils). The paramedics will think you are on drugs. The most stunning study of fluvoxamine ever done was at the Golden Gate Fields racetrack in November 2020, right after the WashU trial was published in JAMA. . . Its really, really common for a small effect, something that looks exciting, to be a statistical fluke when you look at a larger population. Mar. Steve Kirsch: Vaccine Killing Millions, Treatments, VAERS, 5-Month Steve Kirsch Nov 5, 2021 145 92 Here are the key things you should know about fluvoxamine for COVID: It works. National Patterns in Antidepressant Medication Treatment - Home of JAMA ICER Publishes Final Evidence Report and Policy Recommendations on Outpatient Treatments for COVID-19 - ICER. Fluvoxamine at 50mg twice a day for 14 days is a very well-tolerated drug (as long as you avoid caffeine and alcohol) for the treatment of COVID infections. An MIT Technology Review investigation recently revealed how images of a minor and a tester on the toilet ended up on social media. NIH doesnt want you to get the drug since it would compete with Molnupiravir, so fluvoxamine will never make the NIH guidelines. , or the patient is simply sensitive to the drug (50mg twice a day can be too much for some people). Compulsive fiddling with your mask? Completely avoid caffeine, alcohol, tylenol, and benadryl. On his blog, Covid-19 Data Science, he has extensivelyand mercilesslyunpacked Kirschs evidence for the vaccine death claims. The other doctors aren't using it either because they don't know about it or fear doing anything not approved by the CDC for treating COVID. Doctors have no excuse for not prescribing. A very short op-ed arguing for using fluvoxamine against COVID. And he wont talk to you either if you ask nosy questions like Cliff, my risk benefit analysis shows you should be rushing to recommend this drug. In two trials (both published studies in peer reviewed journals with Editor's Choice in both cases), the drug had a 100% effect size in protecting against hospitalization from the respiratory symptoms from COVID. A video presentation by Steve Kirsch, Executive Director of the Covid-19 Early Treatment Fund. If you start later, doctors use higher dosages and compliance becomes a bigger problem. By Steve Kirsch in fluvoxamine Feb 14, 2021 The case for fluvoxamine for treating COVID-19 A very short op-ed arguing for using fluvoxamine against COVID. The External Medicine Podcast - Fluvoxamine as a potential treatment for COVID-19: An Interview with Steve Kirsch. Generally, at 50mg BID x 14, it is very tolerable as long as the patient is instructed to lay off the caffeine. reach out to us at Former Silicon Valley tech executive Steve Kirsch, a philanthropist and Substack author who created the COVID-19 Early Treatment Fund (CETF) to fund researchers working on repurposed drugs, including fluvoxamine, which reduces death from COVID by a factor of 12. Its the gold standard of medical evidence. Medicine has been transformed to doing whatever the NIH/FDA says, regardless of how many lives will be lost. Steve Kirsch -Executive Director at COVID-19 Early Treatment Fund Ivermection study - One .2mg/kg dose a week for prevention "100% success rate whereas those doctors taking placebo had a 59%% infection rate not a typo 237 of 400 docs on placebo got infected vs. 800 docs on Ivermectin none got infected" Antivirals NIH is still unsure whether fluvoxamine should be used to treat COVID (article I did after the TOGETHER trial). This looks ominous, but it harmless. Fluvoxamine public data repository - Google Drive, On Cytokines, Fluvoxamine and COVID-19 Part 1, Jon-Emile S. Kenny MD[@heart_lung] You see, we have a kind of allergy to the past; its our national disease, and the very assurance with which you insist that the past is within the present is l, On Cytokines, Fluvoxamine and COVID-19 Part 2, Jon-Emile S. Kenny MD[@heart_lung] Apocalypse is played out now on a personal scale; it is not in the sky above us, but in our bed. -Mark Doty Introduction With a proposed pathway coupling patho, Effect of Fluvoxamine vs Placebo on Clinical Deterioration in Outpatients With Symptomatic COVID-19, This randomized trial compares the effects of fluvoxamine, a selective serotonin reuptake inhibitor with immunomodulatory effects vs placebo on a composite of dyspnea or pneumonia and oxygen desaturation among adult outpatients with polymerase chain reactionconfirmed mild coronavirus disease 2019 (, Prospective cohort of fluvoxamine for early treatment of COVID-19, Abstract. Every earlier study of fluvoxamine (such as observational studies) showed it work and the mechanism had been shown. Fluvoxamine for COVID: what you need to know - Substack Comparison with molnupiravir. The board members I spoke to say they refused to publicly promote any drugs for off-label use and tried to explain to Kirsch that its incredibly common for exciting results from small trials to disappear in larger ones. The US government accused Janssen of improperly promoting the antipsychotic drug Risperdal to dementia patients despite the drug increasing deaths in the elderly. Those who know Kirsch say this is a typical tactic. If you take fluvoxamine, please avoid caffeine while on the drug. I mean, he really, truly has a heart of gold, Char told me. Soon after his appearance on the DarkHorse podcast, several partners of his most recent startup, M10, expressed concerns about the increasing extremism of Kirschs vaccine views. If you were drowning and we had no known standard of care to save your life and someone had a life preserver which worked 160 times in a row, should we throw them the life preserver or let them drown because we aren't absolutely sure the life preserver's benefit > risk (since just because it worked 160 times in a row and there is a 99.99% chance the effect didn't happen by chance, we could have just gotten lucky). 90,000 people will die in the next 3 weeks alone if we continue to ignore this drug that has caused no harm. It was 25 years ago yesterday that Andrew Wakefield launched the modern iteration of the antivaccine movement.In doing so, he laid down a template that antivax quacks today still follow. Think about it Molnupiravir has a 50% risk reduction whereas fluvxoamine is over 90%. Your best bet is to. Steve Kirsch (@stkirsch) / Twitter - Twitter. It's what's happening He says that Facebook took down one of his posts announcing his appearance on 60 Minutes. Tech Tycoon Steve Kirsch Dangled a COVID Cure and Then Went Full Anti But as Kirsch has clashed with the experts he initially surrounded himself with, hes grown increasingly close to others who share his perspectives on vaccineswho have, in turn, provided a large and receptive audience to his claims about a fluvoxamine conspiracy. What's even worse is that a third of recovered patients from COVID will return to the hospital within 5 months and 1 in 8 die. David Boulware, a researcher at the University of Minnesota, received $125,000 to test the drug against covid. TV NEWS : Search Captions. Borrow Broadcasts : TV Archive : Internet Is that really true? Ive used it personally at 50mg twice a day and experience no adverse events at all. May 16, 2022. The 5 observational studies is icing on the cake. It has shown to be 100% protective of hospitalization in 2 clinical trials. Steve Kirsch is an inventor of the optimal mouse, a Silicon Valley millionaire, and an MIT alum (Class of '80). Where did it go wrong. Early treatment with existing drugs is the fastest, most effective, and lowest. How covid-19 conspiracy videos keep getting millions of views. Quick Summary . Three of the four outpatient trials have been reported out: all were successful. saying that the per-protocol analysis was arbitrary and other excuses. Completely avoid caffeine, alcohol, tylenol, and benadryl. Kirsch is a serial entrepreneur who has spent decades pitching the next big thing, whether optical mice (Mouse Systems), document processing (FrameMaker), search engines (Infoseek), digital. Several other trials around the world are in the final stages, too. . . That trial has now been completed, and the researchers are analyzing their data. This is the gold standard of evidence based medicine, Article about the fluvoxamine rejection (The Verge). But even that didnt last long. The medical community doesnt care about saving lives.
