Renal elimination is negligible. In this study, compared with their level before treatment: Injectafer isnt currently approved for use in children. Tell all of your health care providers that you take Venofer. Follow your doctor's directions carefully. This is why they have a programcalledMedWatchthat encourages Americans to report adversereactions. You would receive 15 mg of Injectafer per kilogram of body weight for each of your two doses. Iron is a vital mineral in the body, central to transporting oxygen around the body in the hemoglobin. Some people are simply allergic to an active ingredient in the medication, so the body responds undesirably. The dosing for iron replacement treatment in pediatric patients less than 2 years old with Peritoneal or Hemodialysis-Dependent CKD or Non-Dialysis-Dependent CKD have not been established. You may report side effects to FDA at 1-800-FDA-1088. The researchers looked to see how well each drug worked to increase peoples hemoglobin level. In clinical studies, diarrhea was reported in less than 1% of people taking Injectafer. For example: Say you weigh 105 pounds (about 48 kilograms). This is a sudden response affecting the entire body, which sometimes happens to people who are allergic to peanuts or beestings. Injectafer isnt a medication that youll take regularly on a schedule. One class of immune checkpoint inhibitors targets the protein PD-1, which acts as a brake to keep the immune system in check. Venofer (iron sucrose injection, USP) Rx Only DESCRIPTION Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. Its because everyones body is different. Injectafer and Feraheme can cause very similar side effects, but some different ones as well. What are the side effects of Venofer? For instance, someone with lowblood pressuremay receive a medication to prevent migraines that lowersblood pressure, this may causeseriousside effects. These lists dont include all possible side effects. Data on file, American Regent, Inc. 1. Fortunately, knowing how longside effectslast can help those suffering know what to donext. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. Venofer: Uses, Taking, Side Effects, Warnings - Medicine.com Consult the product instructions and your pharmacist for storage details. What is the latest research on the form of cancer Jimmy Carter has? These drugs have been compared in a clinical trial of adults with both IDA and CKD who didnt need dialysis. Both Injectafer and Feraheme belong to a class of medications known as iron replacement products. endobj Cancer patients who have anemia and are taking an ESA. Limited data indicate that breastmilk iron is not increased after intravenous infusion of Venofer. Some people may also experience skin irritation from the adhesive tape and other medical equipment used during the procedure. If you have iron deficiency anemia (IDA), consuming moderate amounts of alcohol may be safe, if your doctor tells you its OK. (With IDA, you have a low level of red blood cells thats caused by not having enough iron.). Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Excessive amounts of Venofer may lead to a condition called iron overload, which may be harmful. US residents can call their local poison control center at 1-800-222-1222. Reactions around the injection/infusion site, such as pain, irritation, itching, bleeding, or discoloration after leakage of injection into the skin. If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. Most people do not know how long theirside effectswill last until they go through them. Call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. You may also report side effects at https://www.fda.gov/medwatch. PDF Venofer - Food and Drug Administration Should I avoid certain foods while taking Venofer Vial? A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. Learn how to store and discard medical supplies safely. If you have questions about side effects, call your doctor. Below are examples of these side effects. These pregnancy-related problems include preterm delivery and low birth weight of your infant. Are there side effects from an MRI? - Coalitionbrewing.com You will need frequent medical tests to help your doctor determine how long to treat you with Venofer. Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your . Do not share your drugs with others and do not take anyone else's drugs. endobj People in the study received treatment with either Injectafer or Venofer. Call your doctor for medical advice about side effects. Injectafer and Venofer are both brand-name drugs. <> In clinical trials, serious allergic reactions occurred in 0.1% to 1.5% of people taking Injectafer. (A class of medications describes a group of drugs that work in the same way.). Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Feraheme is also approved to treat IDA in adults who either didnt have improvement in their IDA or had side effects with iron treatment thats taken by mouth. Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. Injectafer can cause low blood levels of phosphorus, which is a condition called hypophosphatemia. But some people have a delayed allergic reaction to certain drugs. Together, you and your doctor can discuss the benefits and risks of treatment options for anemia. PDF Your intravenous iron therapy - Hamilton Health Sciences An example of a drug interaction that many people are not aware of isgrapefruitjuice and statins. Some drugs may have another patient information leaflet. Theseeffects of medicine on thebodycan also lead to medication non-compliance and worsening of themedical conditionthey are meant to treat. Properly discard this product when it is expired or no longer needed. The Injectafer dosage your doctor prescribes will depend on your body weight. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Is Venofer Safe in Breastfeeding - Drlact.com chills difficulty with moving ear congestion or pain flushed, dry skin fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes If youre not sure if youll need to get prior authorization for Injectafer, contact your insurance company. XAO$$d|0tX1`Q$Il#FBm}{#h!/;[bOvvg7 ?tMl7/+wya^,~PA}6&Ftb19OeJ6-a3acKjcpkeGq+7/nO AJJ:Okyfp;xw|]McmK?9"t0m%. Keep all drugs out of the reach of children and pets. All rights reserved. If you miss an appointment for your Injectafer dose, youll need to call your doctors office. For this purpose, Injectafer is approved for use in adults who either: Venofer is also approved to treat IDA. Blood tests may be needed to check for unwanted effects. Terminal half-life ranges from 7 to 12 hours. Venofer (Iron Sucrose Injection): Uses, Dosage, Side Effects - RxList Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. You will be watched closely for at least 30 minutes to make sure you do not have an allergic reaction. Speak to yourhealth careprofessional for medical advice on if the dosage should bereduced. Its not known how common delayed allergic reaction might be in other people using Injectafer. Usually, when drugs may cause an immune system reaction like this, its a concern with your first dose of the drug. Then the study was split into the following two groups, which are discussed below. Treatment with Venofer injections can make it harder for your body to absorb iron medications you take by mouth. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Iron Sucrose (Intravenous Route) Side Effects - Mayo Clinic Drug class: Iron products. Spacing your Injectafer doses out at least 7 days helps to reduce your risk of side effects. Examples of thisinclude: Not allside effectslast forever. As with most drugs, some people can have an allergic reaction after taking Injectafer. But its not known whether this poses any risk to a child whos breastfed. And these two doses need to be separated by at least 7 days. If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. If you notice other effects not listed above, contact your doctor or pharmacist. Tell your doctor if you are pregnant or plan to become pregnant. Venofer and the Venofer logo are registered trademarks of Vifor (International) Inc., Switzerland. Mild side effects of Injectafer can include:*. Also, keep in mind that if your anemia is causing certain symptoms, treatment with Injectafer may help those symptoms go away. Injectafer contains the active drug ferric carboxymaltose. wAd**CgI%"nn{Oa[q{r5 Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. This is why the FDA hasa programcalledMedWatchthat encourages Americans to report adversereactions. If needed, theyll recommend treatment, including certain medications. Here are answers to some frequently asked questions about Injectafer. If these effects continue or worsen, tell your doctor. These tests will help make sure Injectafer is working to treat your iron deficiency anemia (IDA). Brand-name medications usually cost more than generics. Your body then uses the iron from Injectafer to make hemoglobin and new RBCs. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. Injectafer contains the active drug ferric carboxymaltose. Your doctor will be able to see how Venofer is working by reviewing your blood tests. Canada residents can call a provincial poison control center. It belongs to a class of medications known as iron replacement products. Maintain a well-balanced diet, and follow any dietary guidelines as directed by your doctor. Side Effects of Venofer (Iron Sucrose Injection), Warnings, Uses - RxList Both Injectafer and Venofer belong to a class of medications called iron replacement products. Tell your caregivers right away if you have: problems with your dialysis vein access point; high blood pressure - severe headache, blurred vision, pounding in your neck or ears; low blood pressure - a light-headed feeling, like you might pass out; or. As a result, you may not make as much EPO as usual. If you have any questions about Venofer, please talk with your doctor, nurse, pharmacist, or other health care provider. Venofer is used to treat iron deficiency anemia in people with kidney disease. This is not a complete list of side effects and others may occur. Venofer (iron sucrose) Uses, Dosage, Side Effects, FAQ - MedicinesFAQ signs of inflammation in the lining of your stomach - pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. HRT, like other medications, does have some side effects and these are thought to be quite common. The infusion concentration should not be less than 2 mg of Injectafer per mL of solution. In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. Version: 7.01. Iron infusion side effects vary depending on which form is being used. 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